최종호
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- 033-640-2231
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- jhchoi@gwnu.ac.kr
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세부내용
Education
- Ph.D. 2015, Biomedical Science, CHA University
- M.S. 2012, Biomedical Science, CHA University
- B.S. 2010, Marine Bioscience and Technology, Gangneung National University
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Experiences
- Postdoctoral Associate. Feinberg Medical school, Northwestern University, Chicago, USA.
Intellectual properties
- Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway. 1020170040442.
- Pharmaceutical composition for preventing or treating ovary dysfunction or menopausal syndrome comprising placenta-derived stem cells. 1020170022369.
- Pharmaceutical composition for preventing or treating cholestatic liver injury or hyperlipidemia comprising placenta-derived mesenchymal stem cells). 1020200052140.
Journal Articles
- Lee Y, Park G, Kim S, Park S, Choi J. The of e-x-p-r-e-s-s-i-o-n PTTG1 as a biomarker and impact on invasion and growth of oral squamous cell carcinoma. The Korean J Oral and Maxillofacial Pathol. 2023.
- Kim S, Park S, Moon E, Kim GJ, Choi J. Hypoxia disrupt tight junctions and promote metastasis of oral squmous cell carcinoma via loss of par3. Cancer Cell International. 2023.
- Park S, Oh J, Lee SS, Choi J. microRNA-126 promotes the proliferation and migration of oral squamous cell carcinoma cells via HIF-1alpha e-x-p-r-e-s-s-i-o-n. The Korean J Oral and Maxillofacial Pathol. 2023.
- Kim S, Park S, Oh JH, Lee SS, Lee Y, Choi JH. microRNA-18a regulates the metastatic properties of oral squamous cell carcinoma cells via HIF-1 e-x-p-r-e-s-s-i-o-n. BMC Oral Health. 2022.
- Choi JH, Park S, Kim GD, Kim JY, Jun JH, Bae SH, Baik SK, Hwang SG, Kim GJ. Increased phosphatase of regenerating liver-1 by placental stem cells promotes hepatic regeneration in a bile- duct ligated rat model. Cells. 2021.
- Lee SS, Choi JH, Lim SM, Kim GJ, Lee SK, Jeon YK. Alteration of pituitary tumor transforming gene 1 by microRNA-186 and 655 regulates invasion ability of human oral squamous cell carcinoma. Int J Mol Sci. 2021.
- Kim JY, Choi JH*, Kim SH, Park H, Lee D, Kim GJ. Efficacy of gene modification in placenta-derived mesenchymal stem cells based on nonviral electroporation. Int J Stem Cells. 2021.(*: co-first author)
- Choi JH, Seok J, Lim SM, Kim TH, Kim GJ. Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway. Stem Cell Res Ther. 2020.
- Kim JY, Choi JH*, Jun JH, Park S, Jung J, Bae SH, Kim GJ. Enhanced PRL-1 e-x-p-r-e-s-s-i-o-n in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model. Stem Cell Res Ther. 2020. (*: co-first author)
- Jun JH, Kim JY, Choi JH, Lim JY, Kim K, Kim GJ. Exosomes from placenta-derived mesenchymal stem cells are involved in liver regeneration in hepatic failure induced by bile duct ligation. Stem Cell Int. 2020
- Seok J, Park H, Choi JH, Lim JY, Kim KG, Kim GJ. Placenta-derivedmesenchymalstemcellsrestorethe ovary function in an ovariectomized rat model via an antioxidant effect. Antioxidants (Basel). 2020.
- Kim GD*, Choi JH*, Lim SM, Jun JH, Moon JW, Kim JH. Alterations of Il-6/STAT3 signal by Korean mistletoe lectin regulate self-renewal activity of placenta-derived mesenchymal stem cells. Nutrients. 2019. (*: co-first author)
- Choi JH, Troyanovsky RB, Indra I, Mitchell BJ, Troyanovsky SM. Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex. J Cell Biol. 2019 Jul 218(7):2277-2293.
- Indra I, Choi JH, Chen CS, Troyanovsky RB, Shapiro L, Honig B, Troyanosky SM. Spatial and temporal organization of cadherin in punctate adherens junctions. Proc Natl Acad Sci U S A. 2018 May 115(19):E4406-4415.
- Kim SH, Jung J, Cho KJ, Choi JH, Lee HS, Kim GJ, Lee SG. Immunomodulatory Effects of Placenta-derived Mesenchymal Stem Cells on T Cells by Regulation of FoxP3 e-x-p-r-e-s-s-i-o-n. Int J Stem Cells. 2018 Nov 30;11(2):196-204.
- Kim TH*, Choi JH*, Jun Y, Lim SM, Park S, Paek JY, Lee SH, Hwang JY, Kim GJ. 3D-cultured human placenta-derived mesenchymal stem cell spheroids enhance ovary function by inducing folliculogenesis. Sci Rep. 2018 Oct 17;8(1):15313. (*: co-first author)
- Indra I, Choi J, Chen CS, Troyanovsky RB, Shapiro L, Honig B, Troyanovsky SM. Spatial and temporal organization of cadherin in punctate adherens junctions. Proc Natl Acad Sci U S A. 2018 May 8;115(19)
- Lee YB*, Choi JH*, Kim EN, Seok J, Lee HJ, Yoon JH, Kim GJ. Human Chorionic Plate-Derived Mesenchymal Stem Cells Restore Hepatic Lipid Metabolism in a Rat Model of Bile Duct Ligation. Stem Cells Int. 2017;2017:5180579. (*: co-first author)
- Jun JH, Choi JH, Bae SH, Oh SH, Kim GJ. Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation. Clin Mol Hepatol. 2016 Sep;22(3):372-381
- Choi JH, Lee YB, Jung J, Hwang SG, Oh IH, Kim GJ. Hypoxia Inducible Factor-1 Regulates the Migration of Bone Marrow Mesenchymal Stem Cells via Integrin 4. Stem Cells Int. 2016;2016:7932185.
- Choi JH, Lim SM, Yoo YI, Jung J, Park JW, Kim GJ. Microenvironmental Interaction Between Hypoxia and Endothelial Cells Controls the Migration Ability of Placenta-Derived Mesenchymal Stem Cells via 4 Integrin and Rho Signaling. J Cell Biochem. 2016 May;117(5):1145-57.
- Moon JW, Choi JH, Lee SK, Lee YW, Lee JO, Kim N Lee Hj, Seo JS, Kim J, Kim HS, Kim GJ, Park SH. Promoter hypermethylation of membrane type 3 matrix metalloproteinase is associated with cell migration in colorectal adenocarcinoma. Cancer Genet. 2015 May; 261-70.
- Jung J, Moon JW, Choi JH, Lee YW, Park SH, Kim GJ. Epigenetic Alteration of IL-6/STAT3 signaling by placental stem cells promote hepatic regeneration in a rat model with CCl4-induced liver injury. Int J Stem Cells. 2015 May; 79-89.
- Choi JH, Jung JE, Na KH, Cho KJ, Yoon TK, Kim GJ. Effect of mesenchymal stem cells and extracts derived from the placenta on trophoblast invasion and immune responses. Stem Cells Dev. 2014. Jan; 13245.
- Lyu SY*, Choi JH*, Lee HJ, Park WB, Kim GJ. Korean mistletoe lectin promotes proliferation and invasion of trophoblast cells.through regulation of Akt signaling. Reprod Toxicol. 2013 Aug; 39:33-9. (*: co-first author)
- Ran Jung, Choi JH, Hyun Jung Lee, Jin Kyeoung Kim and Gi Jin Kim. Effect of Immortalization-Upregulated Protein-2(IMUP-2) on Cell Death of Trophoblast. Dev. Reprod. 2013 June;17: 99-109.
- Jung J, Choi JH, Lee Y, Park JW, Oh IH, Hwang SG, Kim KS, Jin Kim G. Human Placenta-Derived Mesenchymal Stem Cells Promote Hepatic Regeneration in Ccl(4)-Injured Rat Liver Model Via Increased Autophagic Mechanism. Stem Cells. 2013 Aug:31(8):1584-96
- Na KH*, Choi JH*, Kim CH, Kim KS, Kim GJ. Altered e-x-p-r-e-s-s-i-o-n of norepinephrine transporter and norepinephrine in human placenta cause pre-eclampsia through regulated trophoblast invasion. Clin Exp Reprod Med. 2013 Mar;40(1):12-22. (*: co-first author)
- Choi JH, Lyu SY, Lee HJ, Jung J, Park WB, Kim GJ. Korean mistletoe lectin regulates self-renewal of placenta-derived mesenchymal stem cells via autophagic mechanisms. Cell Prolif. 2012 Oct;45(5):420-9.
- Choi JH, Lee HJ, Yang TH, Kim GJ. Effects of hypoxia inducible factors-1 on autophagy and invasion of trophoblasts. Clin Exp Reprod Med. 2012 Jun;39(2):73-80.
- Na KH, Lee HJ, Choi JH, Eun JW, Nam SW, Yoon TK, Kim GJ. Dynamic alterations in integrin 4 e-x-p-r-e-s-s-i-o-n by hypoxia are involved in trophoblast invasion during early implantation. J Cell Biochem. 2012 Feb;113(2):685-94.
- Lee JS, Jeon SY, Choi JH, Lee YJ, Cha, DH, Kim GJ. Effect of hypoxia-induced XIAP e-x-p-r-e-s-s-i-o-n on apoptosis of trophoblast cell in placenta. Clin Exp Reprod Med. 2010.
- Na KH, Shin KS, Choi JH, Cha DH, Kim GJ. Isolation and characterization of trophoblast stem cells-like cells derived from human term placenta. Dev. Reprod. 2010. 155-162. *: Co-first author